Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700115 | 0.87 | DRD2 (0.50) | DRD2MAOAMAOBAHRDRD4 | |
| SCHEMBL11705425 | 0.82 | MAPT (0.44) | DRD2LMNACYP2C9CYP2C19KDM4E | |
| SCHEMBL11701011 | 0.79 | KDM4E (0.46) | DRD2DRD4DRD3LMNACYP2C9 | |
| SCHEMBL11701831 | 0.77 | DRD2 (0.51) | DRD2AHRDRD4DRD3LMNA | |
| SCHEMBL11700793 | 0.74 | DRD2 (0.52) | DRD2CMA1AHRDRD4DRD3 | |
| SCHEMBL23952333 | 0.73 | DRD2 (0.53) | WDR91DRD2MAOAMAOBCMA1 | |
| SCHEMBL9833960 | 0.71 | DRD2 (0.46) | DRD2AHRDRD4DRD3LMNA | |
| SCHEMBL6324288 | 0.71 | CCNB2 (0.49) | WDR91CMA1AHRMAPTCCNB2 | |
| SCHEMBL19704714 | 0.69 | ALDH1A1 (0.43) | DRD2DRD4DRD3LMNACYP2C9 | |
| SCHEMBL624585 | 0.69 | CCNB2 (0.54) | WDR91DRD2CMA1AHRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033995-A | D-homo steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |
| US-4006161-A | SEDATIVE, TRANQUILIZER | ELI LILLY AND COMPANY (US) | 1977-02-01 | — | — | US | disclosed |