Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.71 |
| ▸ | CA2 | P00918 | 5/20 | 0.71 |
| ▸ | CA9 | Q16790 | 4/20 | 0.71 |
| ▸ | CA12 | O43570 | 3/20 | 0.71 |
| ▸ | CA7 | P43166 | 3/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701606 | 0.94 | CA1 (0.65) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11703950 | 0.91 | ESR1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11700494 | 0.88 | SMN1; SMN2 (0.69) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11699178 | 0.88 | CA1 (0.57) | CA1CA2CA9CA12CA7 | |
| SCHEMBL87450 | 0.87 | CA1 (0.83) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11839699 | 0.86 | MAPT (0.69) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29504635 | 0.85 | CA1 (0.79) | CA1CA2CA9CA12CA7 | |
| SCHEMBL21440358 | 0.85 | CA1 (0.79) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30271267 | 0.85 | CA1 (0.79) | CA1CA2CA9CA12CA7 | |
| SCHEMBL27647572 | 0.85 | CA1 (0.79) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4043976-A | N,N'-DIBENZOYLHYDRAZINE DERIVATIVE | UBE INDUSTRIES, LTD. (JA) | 1977-08-23 | — | — | US | claimed |
| US-4043976-A | N,N'-DIBENZOYLHYDRAZINE DERIVATIVE | UBE INDUSTRIES, LTD. (JA) | 1977-08-23 | — | — | US | disclosed |