SCHEMBL11699178

SCHEMBL11699178

CCOC(=O)c1ccc(C(=O)NNC(=O)c2ccc(C(=O)OCC(C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA9 Q16790 2/20 0.57
CA12 O43570 1/20 0.57
ESR1 P03372 1/20 0.57
CA7 P43166 1/20 0.57
ESR2 Q92731 1/20 0.57
CA14 Q9ULX7 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
GAA P10253 1/20 0.52
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAOA P21397 1/20 0.51
MAPT P10636 2/20 0.50
TSHR P16473 1/20 0.50
GPR35 Q9HC97 1/20 0.48
PLA2G1B P04054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11701351 0.94 ALDH1A1 (0.53) RAB9ANPC1GAAMAPTTSHR
SCHEMBL5167985 0.90 CA12 (0.63) CA1CA2CA9CA12ESR1
SCHEMBL11765818 0.89 MAPT (0.54) CA1CA2CA9CA12CA7
SCHEMBL11699263 0.88 CA1 (0.71) CA1CA2CA9CA12ESR1
SCHEMBL11702741 0.88 ALDH1A1 (0.59) ESR1SMN1; SMN2RAB9ANPC1GAA
Ethylparaben SCHEMBL5971569 0.87 CA12 (0.77) CA1CA2CA9CA12ESR1
SCHEMBL11702063 0.86 CA12 (0.56) CA1CA2CA9CA12CA7
SCHEMBL11701606 0.83 CA1 (0.65) CA1CA2CA9CA12ESR1
SCHEMBL110051 0.83 ALDH1A1 (0.64) CA1CA2CA9CA12ESR1
Benzoic Acid 2-Methylpropyl Ester SCHEMBL31190186 0.82 ALDH1A1 (0.61) CA1CA2CA9CA12ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4043976-A N,N'-DIBENZOYLHYDRAZINE DERIVATIVE UBE INDUSTRIES, LTD. (JA) 1977-08-23 US disclosed