Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 2/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701929 | 1.00 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL11702145 | 1.00 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL10394216 | 1.00 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL31482443 | 0.98 | ADORA2B (0.81) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL4384952 | 0.95 | ADORA2B (0.78) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL16120983 | 0.95 | ADORA2B (0.85) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL16121000 | 0.95 | ADORA2B (0.85) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL16120982 | 0.95 | ADORA2B (0.85) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL16120999 | 0.95 | ADORA2B (0.85) | ADORA2BMAPK1RXFP1ADORA2ALMNA | |
| SCHEMBL16120989 | 0.95 | ADORA2B (0.85) | ADORA2BMAPK1RXFP1ADORA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | claimed |
| US-4002756-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-4000132-A | REACTION WITH CARBOXYLIC ACID, PHOSGENE, OR THIONYL CHLORIDE | INTERX RESEARCH CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |