Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 11/20 | 0.85 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16120982 | 1.00 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120989 | 1.00 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120999 | 1.00 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120983 | 1.00 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL19969384 | 1.00 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120975 | 0.98 | ADORA2B (0.88) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL10394216 | 0.95 | ADORA2B (0.78) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL11699832 | 0.95 | ADORA2B (0.78) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL11702145 | 0.95 | ADORA2B (0.78) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL11701929 | 0.95 | ADORA2B (0.78) | ADORA2BRXFP1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10226467-B2 | Compounds for the treatment of myotonic dystrophy | UNIVERSITAT DE VALENCIA (ES) | 2019-03-12 | — | — | US | disclosed |
| US-20170349317-A1 | GAS BARRIER ENHANCING ADDITIVES AND METHODS | THE COCA-COLA COMPANY | 2017-12-07 | — | — | US | disclosed |
| US-20170349317-A1 | GAS BARRIER ENHANCING ADDITIVES AND METHODS | THE COCA-COLA COMPANY | 2017-12-07 | — | — | US | disclosed |
| US-20170312285-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | SELABTEC SCIENCES, SL (ES) | 2017-11-02 | — | — | US | disclosed |
| US-20170312285-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | SELABTEC SCIENCES, SL (ES) | 2017-11-02 | — | — | US | disclosed |
| US-20170304309-A1 | CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2 | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S.A. (ES) | 2017-10-26 | — | — | US | disclosed |
| US-20170304309-A1 | CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2 | INSTITUT UNIV. DE CIENCIA I TECNOLOGIA, S.A. (ES) | 2017-10-26 | — | — | US | disclosed |
| US-9764872-B2 | Gas barrier enhancing additives and methods | THE COCA-COLA COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| US-9764872-B2 | Gas barrier enhancing additives and methods | THE COCA-COLA COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| WO-2016075285-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | UNIVERSITAT DE VALÈNCIA (ES) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016075288-A1 | CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2 | UNIVERSITAT DE VALÈNCIA (ES) | 2016-05-19 | — | — | WO | disclosed |
| EP-3020403-A1 | Compounds for the treatment of myotonic dystrophy | Universitat de Valéncia (ES) | 2016-05-18 | — | — | EP | disclosed |
| EP-3020404-A1 | Caffeine for the treatment of myotonic dystrophy type 1 and type 2 | Universitat de Valéncia (ES) | 2016-05-18 | — | — | EP | disclosed |
| US-20160031583-A1 | GAS BARRIER ENHANCING ADDITIVES AND METHODS | CSPC INNOVATION PHARMACEUTICAL CO., LTD. (CN) | 2016-02-04 | — | — | US | disclosed |
| US-20160031583-A1 | GAS BARRIER ENHANCING ADDITIVES AND METHODS | CSPC INNOVATION PHARMACEUTICAL CO., LTD. (CN) | 2016-02-04 | — | — | US | disclosed |
| WO-2014152788-A1 | GAS BARRIER ENHANCING ADDITIVES AND METHODS | THE COCA-COLA-COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304309-A1 | CAFFEINE FOR THE TREATMENT OF MYOTONIC DYSTROPHY TYPE 1 AND TYPE 2 | SMN1; SMN2, TDP2, MTPN | ADORA2B 972/4885RXFP1 1677/4885MAPK1 569/4885 |
| US-20170312285-A1 | COMPOUNDS FOR THE TREATMENT OF MYOTONIC DYSTROPHY | SMN1; SMN2, CPT1B, MTPN | ADORA2B 1199/4885RXFP1 2764/4885MAPK1 1363/4885 |
| US-10226467-B2 | Compounds for the treatment of myotonic dystrophy | SMN1; SMN2, CPT1B, MTPN | ADORA2B 1199/4885RXFP1 2764/4885MAPK1 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.