SCHEMBL11700348

SCHEMBL11700348

O=C(O)c1cccc2c(S(=O)(=O)Oc3ccc(Oc4ccccc4)cc3)ccc(C(=O)O)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CYSLTR1 Q9Y271 1/20 0.42
DHODH Q02127 1/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MMP2 P08253 2/20 0.40
MMP13 P45452 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11703859 0.95 NR4A1 (0.45) CA1CA2NR4A1NR4A2NR4A3
SCHEMBL11701384 0.90 MEN1 (0.49) MCL1CA1CA2CA9DHODH
SCHEMBL11697970 0.87 TDP1 (0.47) MCL1CA1CA2CA9NR4A1
SCHEMBL11703793 0.87 LMNA (0.41) MCL1CA1CA2CA9NR4A1
SCHEMBL11703884 0.87 KMT2A (0.43) CA1CA2CA9NR4A1NR4A2
SCHEMBL11703824 0.87 BCL2L1 (0.43) MCL1CA1CA2CA9MEN1
SCHEMBL11704143 0.87 ALDH1A1 (0.39) MCL1CA1CA2CA9NR4A1
SCHEMBL11702285 0.86 PTPN1 (0.40) NR4A1NR4A2NR4A3MEN1KMT2A
SCHEMBL11700529 0.85 NR4A1 (0.45) MCL1CA1CA2CA9NR4A1
SCHEMBL11704718 0.84 MCL1 (0.41) MCL1CA1CA2CA9DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4024144-A SULFONIC ACID GROUPS BAYER AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed