Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465968 | 0.81 | TDP1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL11234473 | 0.80 | TSHR (0.47) | PPARGPPARAIDO1TDO2TSHR | |
| SCHEMBL6559772 | 0.77 | TSHR (0.44) | PPARGPPARAIDO1TDO2TSHR | |
| SCHEMBL11702182 | 0.77 | PPARG (0.41) | PPARGPPARAIDO1TDO2ALDH1A1 | |
| SCHEMBL11210654 | 0.77 | PPARG (0.48) | PPARGPPARATSHRALDH1A1L3MBTL1 | |
| SCHEMBL3628714 | 0.76 | LTA4H (0.33) | TSHR | |
| SCHEMBL1466000 | 0.76 | LTA4H (0.33) | TSHR | |
| SCHEMBL3628711 | 0.76 | LTA4H (0.33) | TSHR | |
| SCHEMBL9546526 | 0.76 | L3MBTL1 (0.55) | PPARGPPARATSHRALDH1A1L3MBTL1 | |
| SCHEMBL195629 | 0.74 | LTA4H (0.43) | TSHRALDH1A1L3MBTL1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025570-A | REACTION OF ETHYLENE WITH 1,3-DIENE; CATALYST OF NICKEL, HYDROCARBYLALUMINUM HALIDE, AND ARYL PHOSPHINITE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-05-24 | — | — | US | disclosed |