Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340685 | 0.98 | MEN1 (0.60) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11763986 | 0.94 | LMNA (0.52) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL5201000 | 0.93 | MEN1 (0.60) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11759786 | 0.92 | MEN1 (0.50) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL16074981 | 0.91 | MEN1 (0.58) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11668697 | 0.89 | ALOX15 (0.47) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL14047325 | 0.88 | MEN1 (0.55) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL9403709 | 0.88 | MEN1 (0.55) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL10824443 | 0.85 | MEN1 (0.49) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL14047326 | 0.85 | MEN1 (0.56) | LMNAMEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032588-A | REACTING KETONE WITH ACETYLENE, HYDROCRACKING | SHISEIDO CO., LTD. (JA) | 1977-06-28 | — | — | US | disclosed |
| US-4011277-A | PREPARATION OF SQUALANE BY HYDROGENOLYSIS | KURARAY CO., LTD. (JA) | 1977-03-08 | — | — | US | disclosed |
| US-3981930-A | Diacetylene diol derivatives and process for preparing the same | KURARAY CO., LTD. (JA) | 1976-09-21 | — | — | US | disclosed |
| US-3975451-A | Diols and process for preparation thereof | KURARAY CO., LTD. (JA) | 1976-08-17 | — | — | US | disclosed |