Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898541 | 0.86 | HSP90AA1 (0.45) | TDP1HSP90AA1HSP90B1HKDC1CYP1A2 | |
| SCHEMBL11240568 | 0.79 | TDP1 (0.39) | TDP1HSP90AA1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11420097 | 0.70 | SMN1; SMN2 (0.35) | TDP1HSP90AA1HSP90B1CYP1A2SMN1; SMN2 | |
| SCHEMBL11412094 | 0.70 | HSP90AA1 (0.44) | TDP1HSP90AA1HSP90B1HKDC1SMN1; SMN2 | |
| SCHEMBL11252306 | 0.69 | TDP1 (0.40) | TDP1SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL12242131 | 0.68 | TDP1 (0.46) | TDP1SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL28654605 | 0.68 | TDP1 (0.46) | TDP1SMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL11241564 | 0.68 | TDP1 (0.42) | TDP1HSP90AA1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12220409 | 0.67 | TDP1 (0.45) | TDP1CYP1A2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11238262 | 0.67 | TDP1 (0.38) | TDP1CYP1A2SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008043-A | Diphenylamines for dyeing keratinic fibers | L'OREAL (FR) | 1977-02-15 | — | — | US | disclosed |