SCHEMBL11238262

SCHEMBL11238262

CC(=O)NC1=CC(=O)C=CC1=N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
LMNA P02545 2/20 0.36
S100A4 P26447 1/20 0.34
GAA P10253 3/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PKM P14618 1/20 0.33
ALOX15 P16050 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 2/20 0.32
MIF P14174 1/20 0.32
CA12 O43570 1/20 0.32
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11234960 0.80 PEPD (0.32) ALDH1A1NPC1
SCHEMBL1603211 0.79 TDP1 (0.43) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL11309696 0.73 TDP1 (0.36) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL11252306 0.71 TDP1 (0.40) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL19390283 0.69 LMNA (0.38) TDP1MEN1KMT2ALMNAGAA
SCHEMBL11241564 0.69 TDP1 (0.42) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL11240568 0.69 TDP1 (0.39) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL11700504 0.67 TDP1 (0.37) TDP1MEN1KMT2AS100A4GAA
SCHEMBL6295304 0.67 TDP1 (0.44) TDP1MEN1KMT2ALMNAS100A4
SCHEMBL15426748 0.67 TDP1 (0.44) TDP1MEN1KMT2ALMNAS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4361516-A N-Monosubstituted indoanilines SOCIETE ANONYME DITE: L'OREAL (FR) 1982-11-30 US disclosed
US-4008999-A N,N-dialkylamino diphenylamines for dyeing keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-22 US disclosed
US-4007747-A HAIR DYES SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-15 US disclosed
US-4008043-A Diphenylamines for dyeing keratinic fibers L'OREAL (FR) 1977-02-15 US disclosed