Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700504 | 0.86 | TDP1 (0.37) | HSP90AA1HSP90B1KDM4EALDH1A1MEN1 | |
| SCHEMBL11412094 | 0.84 | HSP90AA1 (0.44) | HSP90AA1HSP90B1KDM4EALDH1A1MEN1 | |
| SCHEMBL30092600 | 0.76 | ERBB2 (0.45) | HSP90AA1HSP90B1KDM4EALDH1A1MEN1 | |
| SCHEMBL11420097 | 0.76 | SMN1; SMN2 (0.35) | HSP90AA1HSP90B1ALDH1A1MEN1KMT2A | |
| SCHEMBL28654605 | 0.75 | TDP1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL12242131 | 0.75 | TDP1 (0.46) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL49737 | 0.74 | ERBB2 (0.62) | KDM4EALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL11410493 | 0.73 | HSP90AA1 (0.39) | HSP90AA1HSP90B1KDM4EALDH1A1MEN1 | |
| SCHEMBL12220409 | 0.73 | TDP1 (0.45) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL11281004 | 0.73 | TDP1 (0.45) | HSP90AA1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | claimed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| US-6179883-B1 | USING 2-IMINO-2,3-DIHYDRO-1H-INDOLE MIXTURE | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |
| EP-0826668-B1 | Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions | OREAL (FR) | 1999-06-30 | — | — | EP | disclosed |
| EP-0826668-A1 | Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions | L'OREAL (FR) | 1998-03-04 | — | — | EP | disclosed |
| EP-0603322-B1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | OREAL (FR) | 1996-12-11 | — | — | EP | disclosed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0603322-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. | OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005018-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | L'OREAL (FR) | 1993-03-18 | — | — | WO | disclosed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| EP-0376776-B1 | PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE | L'OREAL (FR) | 1992-09-23 | — | — | EP | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | disclosed |