Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293223 | 0.98 | — | — | |
| Iodide SCHEMBL7334458 | 0.96 | — | — | |
| Bromide SCHEMBL9294581 | 0.88 | L3MBTL1 (0.48) | — | |
| SCHEMBL10292999 | 0.85 | — | — | |
| Bromide SCHEMBL11347475 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL4790582 | 0.76 | ALDH1A1 (0.53) | — | |
| Bromide SCHEMBL29369752 | 0.76 | ALDH1A1 (0.49) | — | |
| SCHEMBL28703365 | 0.76 | — | — | |
| SCHEMBL10811418 | 0.76 | — | — | |
| SCHEMBL11132210 | 0.75 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29358-E | ANTI-MALARIA AND ANTI-TUBERCULOSIS AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-08-16 | — | — | US | disclosed |