SCHEMBL1170107

SCHEMBL1170107

C=C(CCCCCCCCCCCS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.54
TBXAS1 P24557 2/20 0.43
HDAC3 O15379 8/20 0.40
HDAC1 Q13547 8/20 0.40
HDAC2 Q92769 8/20 0.40
HDAC10 Q969S8 8/20 0.40
HDAC11 Q96DB2 8/20 0.40
HDAC8 Q9BY41 8/20 0.40
HDAC6 Q9UBN7 8/20 0.40
HDAC4 P56524 7/20 0.40
HDAC7 Q8WUI4 7/20 0.40
HDAC9 Q9UKV0 7/20 0.40
HDAC5 Q9UQL6 7/20 0.40
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
TET2 Q6N021 2/20 0.33
GSTK1 Q9Y2Q3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4335018 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL15456556 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL8332559 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL8332021 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL3324860 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL4332041 1.00 FOLH1 (0.54) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL2026776 0.98 FOLH1 (0.56) FOLH1TBXAS1HDAC3HDAC1HDAC2
SCHEMBL2022931 0.90
SCHEMBL1860769 0.87 TBXAS1 (0.50) TBXAS1HDAC11LMNATSHRNFKB1
SCHEMBL3125930 0.87 TBXAS1 (0.50) TBXAS1HDAC11LMNATSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733114-B1 DENTAL MILL BLANK AND METHOD FOR PRODUCING SAME KURARAY NORITAKE DENTAL INC (JP) 2024-04-17 EP disclosed
US-11707346-B2 Dental mill blank and method for producing same KURARAY NORITAKE DENTAL INC. (JP) 2023-07-25 US disclosed
US-20200360120-A1 DENTAL MILL BLANK AND METHOD FOR PRODUCING SAME KURARAY NORITAKE DENTAL INC. (JP) 2020-11-19 US disclosed
EP-3733114-A1 DENTAL MILL BLANK AND METHOD FOR PRODUCING SAME Kuraray Noritake Dental Inc. (JP) 2020-11-04 EP disclosed
WO-2020138472-A1 DENTAL MILL BLANK HAVING OPTIMIZED COLOR TONE クラレノリタケデンタル株式会社 2020-07-02 WO disclosed
EP-3556814-A1 METHOD FOR PRODUCING SURFACE-TREATED COLORED INORGANIC PARTICLES Kuraray Noritake Dental Inc. (JP) 2019-10-23 EP disclosed
US-20190315970-A1 METHOD FOR PRODUCING SURFACE-TREATED COLORED INORGANIC PARTICLES KURARAY NORITAKE DENTAL INC. (JP) 2019-10-17 US disclosed
US-9089482-B2 Dental mill blank KURARAY NORITAKE DENTAL INC. (JP) 2015-07-28 US disclosed
US-20130172441-A1 DENTAL MILL BLANK KURARAY NORITAKE DENTAL INC. (JP) 2013-07-04 US disclosed
US-8436078-B2 Dental composition and composite resin KURARAY NORITAKE DENTAL INC. (JP) 2013-05-07 US disclosed
US-20110046260-A1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY MEDICAL INC. (JP) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046260-A1 DENTAL COMPOSITION AND COMPOSITE RESIN CAD, ITGB5, ITGA5 FOLH1 4759/4885TBXAS1 4622/4885HDAC3 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.