Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26085068 | 0.84 | TSHR (0.55) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL909852 | 0.84 | TSHR (0.55) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL28724211 | 0.81 | TSHR (0.54) | TSHRRORCUSP2HPGDHSD17B10 | |
| Benzene SCHEMBL1840471 | 0.81 | TSHR (0.57) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL28647277 | 0.79 | TSHR (0.50) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL10997664 | 0.78 | TSHR (0.53) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL27929169 | 0.78 | TSHR (0.44) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL10779462 | 0.76 | TSHR (0.45) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL10780955 | 0.76 | TSHR (0.50) | TSHRRORCUSP2HPGDHSD17B10 | |
| SCHEMBL355986 | 0.74 | TSHR (0.70) | TSHRRORCUSP2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013473-A | THERMOGRAPHY, SUBSTITUTED PHENOL REDUCING AGENT | AGFA-GEVAERT N.V. (BE) | 1977-03-22 | — | — | US | disclosed |