Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17429416 | 0.85 | TSHR (0.53) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL909852 | 0.82 | TSHR (0.55) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL10997664 | 0.81 | TSHR (0.53) | TSHRRORCUSP2ALDH1A1GAA | |
| Benzene SCHEMBL1840471 | 0.79 | TSHR (0.57) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11682514 | 0.77 | TSHR (0.50) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL18885180 | 0.77 | RORC (0.58) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL11701337 | 0.76 | TSHR (0.52) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL21064683 | 0.76 | TSHR (0.57) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL28724211 | 0.75 | TSHR (0.54) | TSHRRORCUSP2ALDH1A1GAA | |
| SCHEMBL560269 | 0.73 | TSHR (0.70) | TSHRRORCUSP2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4669544-A | TREATMENT WITH SULFUR TRIOXIDE | DOWELL SCHLUMBERGER INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |