Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701545 | 1.00 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1IDO1 | |
| SCHEMBL17862090 | 0.85 | NFE2L2 (0.59) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL73226 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL9353695 | 0.76 | NFE2L2 (0.54) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL8548176 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL7428113 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL3885395 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL10423140 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL2451125 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL11699628 | 0.76 | AHR (0.48) | NFE2L2PTGS1IDO1FBP1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |