Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548176 | 1.00 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL17862090 | 0.85 | NFE2L2 (0.59) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL1046101 | 0.76 | CYP2C19 (0.42) | GRIK1GRIK2 | |
| SCHEMBL11701550 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL73226 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL10423140 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL5315827 | 0.76 | APP (0.43) | APPPTGS1 | |
| SCHEMBL3885395 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL11701545 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL2451125 | 0.76 | NFE2L2 (0.50) | NFE2L2HSD11B1APPPTGS1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422537-B1 | Cyclohexenone compounds, process for their preparation and their use as herbicides or plant growth regulators | BASF AG (DE) | 1994-05-11 | — | — | EP | claimed |
| EP-0422537-A1 | Cyclohexenone compounds, process for their preparation and their use as herbicides or plant growth regulators | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | claimed |
| CN-1370176-A | Subsstituted heterocycle fused gamma-carbolines | BRISTOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | disclosed |
| EP-1192165-A2 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES | Bristol-Myers Squibb Pharma Company (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000077010-A2 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6066756-A | FUNGICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| EP-0561853-B1 | HERBICIDAL AGENTS CONTAINING SUBSTITUTED 2-AMINOTHIOPHENE | BASF AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| EP-0561830-B1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1997-04-16 | — | — | EP | disclosed |
| CN-1134420-A | 5-tetrahydropyranone cyclohexenone oxime ethers and their use as herbicides | BASF AG (DE) | 1996-10-30 | — | — | CN | disclosed |
| US-5561100-A | PLANT SAFENING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-01 | — | — | US | disclosed |
| US-5523462-A | HERBICIDES; PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0561836-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| WO-1993008153-A1 | CYCLOHEXENONE DERIVATES USED AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |
| WO-1992010094-A1 | HERBICIDAL AGENTS CONTAINING SUBSTITUTED 2-AMINOTHIOPHENE | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992010480-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992010489-A1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992010500-A1 | PYRIDO-ANELLATED 4-OXO-4H-BENZOPYRANS, A METHOD OF PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |
| US-5085689-A | Preemergence and postemergence treatment | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| EP-0422537-A1 | Cyclohexenone compounds, process for their preparation and their use as herbicides or plant growth regulators | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0102034-A1 | Spiro(2H-1,4-benzodioxepin-3(5H)4'-piperidine and 3'-pyrrolidino) compounds, a process for preparing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-03-07 | — | — | EP | disclosed |