Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696644 | 0.85 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL9374363 | 0.83 | CYP19A1 (0.60) | HMOX1CYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL9373635 | 0.83 | CYP19A1 (0.60) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10816487 | 0.82 | HMOX1 (0.91) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10197408 | 0.82 | HMOX1 (0.91) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL11612301 | 0.81 | CYP19A1 (0.58) | CYP19A1CYP11B1CYP11B2 | |
| Brolaconazole SCHEMBL2107423 | 0.81 | HMOX1 (0.61) | HMOX1CYP19A1CYP11B1CYP11B2IDO1 | |
| SCHEMBL11700389 | 0.81 | CYP17A1 (0.50) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11696160 | 0.80 | CYP17A1 (0.50) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11703283 | 0.80 | CYP19A1 (0.63) | HMOX1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |