Brolaconazole

Brolaconazole

SCHEMBL2107423

Brc1ccc(C(Cn2ccnc2)c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HMOX1 P09601 1/20 0.61
CYP19A1 P11511 4/20 0.58
CYP11B1 P15538 1/20 0.53
CYP11B2 P19099 1/20 0.53
HMOX2 P30519 1/20 0.51
IDO1 P14902 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10652258 0.90 CYP19A1 (0.69) CYP19A1CYP11B1CYP11B2HMOX2
SCHEMBL10650023 0.84 CYP19A1 (0.66) CYP19A1CYP11B1CYP11B2HMOX2
SCHEMBL10648284 0.84 CYP19A1 (0.74) CYP19A1CYP11B1CYP11B2HMOX2IDO1
SCHEMBL11701649 0.81 HMOX1 (0.64) HMOX1CYP19A1CYP11B1CYP11B2IDO1
SCHEMBL10197408 0.79 HMOX1 (0.91) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL10816487 0.79 HMOX1 (0.91) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL11450792 0.79 CYP19A1 (0.59) CYP19A1CYP11B1CYP11B2
SCHEMBL10647315 0.79 CYP19A1 (0.58) CYP19A1HMOX2
SCHEMBL6971977 0.77 HMOX1 (0.63) HMOX1CYP19A1CYP11B1CYP11B2
SCHEMBL27956564 0.77 HMOX1 (0.59) HMOX1CYP19A1CYP11B1CYP11B2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
CN-101099463-A Agrochemical composition, use for agrochemical composition and using method OXITENO SA IND & COM (BR) 2008-01-09 CN claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20040254182-A1 Enhanced propertied pharmaceuticals ROHM AND HAAS COMPANY 2004-12-16 US claimed
CN-1441790-A Enhanced propertied pharmaceuticals ROHM & HAAS (US) 2003-09-10 CN claimed
EP-1272463-A1 ENHANCED PROPERTIED PHARMACEUTICALS ROHM AND HAAS COMPANY (US) 2003-01-08 EP claimed
WO-2001054481-A2 ENHANCED PROPERTIED PHARMACEUTICALS ROHM AND HAAS COMPANY (US) 2001-08-02 WO claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
CN-110461143-A Seed treatment compositions MONSANTO TECHNOLOGY LLC 2019-11-15 CN disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
WO-2001054481-A2 ENHANCED PROPERTIED PHARMACEUTICALS ROHM AND HAAS COMPANY (US) 2001-08-02 WO disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
EP-0276583-A1 Imidazole derivatives, processes for their preparation and their fungicidal properties Instituto de Investigacion Y Desarrollo Quimico Biologico S.A. (ES) 1988-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254182-A1 Enhanced propertied pharmaceuticals ABCB1, ABCB11, ABCG2 HMOX1 901/4885CYP19A1 946/4885CYP11B1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.