Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990902 | 0.77 | ALDH1A1 (0.32) | SMN1; SMN2ALDH1A1ENPP2LPAR2 | |
| SCHEMBL3416196 | 0.75 | TSHR (0.63) | SMN1; SMN2ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL12372972 | 0.75 | TSHR (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL779433 | 0.73 | TRPM8 (0.45) | LPAR2 | |
| SCHEMBL11696130 | 0.73 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TSHRPLA2G2C | |
| SCHEMBL17636214 | 0.72 | TSHR (0.55) | SMN1; SMN2ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL13431264 | 0.72 | TSHR (0.55) | SMN1; SMN2ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL4158403 | 0.72 | PPARD (0.39) | ALDH1A1TDP1PLA2G2C | |
| SCHEMBL16427895 | 0.71 | LPAR3 (0.50) | LPAR2 | |
| SCHEMBL4164673 | 0.71 | PPARD (0.34) | ALDH1A1TSHRPLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048374-A | Functional organophosphonic acid esters as preservative adhesion promoting agents and coating for metals | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4029679-A | PROTECTIVE METAL COATING | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-06-14 | — | — | US | disclosed |