Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL11058611 | 0.98 | LMNA (0.55) | LMNATSHRALOX12ACHECYP1A2 | |
| Toluene SCHEMBL28179351 | 0.89 | LMNA (0.46) | LMNATSHRALOX12ACHECYP1A2 | |
| Toluene SCHEMBL28002841 | 0.86 | LMNA (0.42) | LMNATSHRALOX12ACHECYP1A2 | |
| Toluene SCHEMBL28576252 | 0.85 | LMNA (0.46) | LMNATSHRALOX12ACHECYP1A2 | |
| P-Xylene SCHEMBL25188894 | 0.84 | CYP1A2 (0.53) | LMNATSHRALOX12ACHECYP1A2 | |
| Toluene SCHEMBL11299292 | 0.83 | LMNA (0.55) | LMNATSHRALOX12ACHECYP1A2 | |
| Toluene SCHEMBL2034748 | 0.83 | CYP1A2 (0.53) | LMNATSHRALOX12ACHECYP1A2 | |
| M-Xylene SCHEMBL28286712 | 0.81 | ACHE (0.57) | LMNATSHRACHECYP1A2KDM4E | |
| Toluene SCHEMBL744674 | 0.80 | TSHR (0.58) | LMNATSHRALOX12ACHEKDM4E | |
| O-Xylene SCHEMBL27667248 | 0.80 | CYP1A2 (0.59) | LMNATSHRACHECYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005035-A | Composition for reinforced and filled high density rigid polyurethane foam products and method of making same | TECNIK INTERNATIONAL CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |