SCHEMBL11701972

SCHEMBL11701972

C=CN(CCCC)C(=O)Cl

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TP53 P04637 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
TSHR P16473 6/20 0.37
HPGD P15428 2/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
FAAH O00519 1/20 0.36
ZDHHC20 Q5W0Z9 2/20 0.35
ZDHHC2 Q9UIJ5 2/20 0.35
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
EP300 Q09472 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11704289 0.92 ZDHHC20 (0.44) ALDH1A1TP53TSHRFAAHZDHHC20
SCHEMBL11707427 0.92 ZDHHC20 (0.44) ALDH1A1TP53TSHRFAAHZDHHC20
SCHEMBL11702565 0.86
SCHEMBL11107651 0.83 CA12 (0.39) ALDH1A1CA12CA1CA9TSHR
SCHEMBL927505 0.83 CA12 (0.39) ALDH1A1CA12CA1CA9TSHR
SCHEMBL11688049 0.83 ALDH1A1 (0.39) ALDH1A1TP53CA12CA1CA9
SCHEMBL2950233 0.81 CA12 (0.38) ALDH1A1CA12CA1CA9TSHR
SCHEMBL29015023 0.81 ZDHHC20 (0.45) ALDH1A1CA12CA1CA9TSHR
SCHEMBL11177351 0.79
SCHEMBL7617429 0.79 ALDH1A1 (0.48) ALDH1A1TP53CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4038311-A PRODUCTION OF N-(1-ALKENYL)-CARBAMYL CHLORIDES BASF AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed