Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677471 | 0.74 | BRD4 (0.39) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL17645580 | 0.74 | BRD4 (0.39) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL6964192 | 0.72 | BRD4 (0.41) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL20499842 | 0.70 | CYP2B6 (0.36) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL28346284 | 0.70 | NPC1 (0.41) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL17645571 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL1626841 | 0.66 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL329316 | 0.66 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL1178246 | 0.65 | BRD4 (0.48) | ALDH1A1HSD17B10L3MBTL1GAATSHR | |
| SCHEMBL29552661 | 0.65 | ESR1 (0.38) | ALDH1A1MAPTHSD17B10SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038470-A | METHOD FOR PREPARATION OF POLYMERS WHICH CONTAIN N-ACYLLACTAM GROUPS | CESKOSLOVENSKA AKADEMIE VED (CS) | 1977-07-26 | — | — | US | disclosed |