SCHEMBL6964192

SCHEMBL6964192

C[Si](C)(C)N1CCCCC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.41
BRD2 P25440 1/20 0.41
PIK3CD O00329 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7677471 0.98 BRD4 (0.39) BRD4BRD2PIK3CDL3MBTL1LMNA
SCHEMBL1178246 0.93 BRD4 (0.48) BRD4BRD2PIK3CDL3MBTL1LMNA
SCHEMBL17645580 0.84 BRD4 (0.39) BRD4BRD2PIK3CDL3MBTL1ALDH1A1
Caprolactam SCHEMBL8195395 0.82 CRBN (0.52)
SCHEMBL17645571 0.78 ALDH1A1 (0.37) BRD4BRD2L3MBTL1ALDH1A1MAPT
SCHEMBL10417960 0.77
SCHEMBL22680910 0.75 TSHR (0.31) ALDH1A1
SCHEMBL22680928 0.74 BRD4 (0.40) BRD4BRD2PIK3CDL3MBTL1LMNA
SCHEMBL8075291 0.72
SCHEMBL11701973 0.72 ALDH1A1 (0.45) L3MBTL1ALDH1A1MAPTHSD17B10MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63264503-A None JP disclosed
US-8808404-B2 Method for making electrochemical cells BASF CORPORATION (US) 2014-08-19 US disclosed
US-8808404-B2 Method for making electrochemical cells BASF CORPORATION (US) 2014-08-19 US disclosed
US-20120291264-A1 Nitrogen Silylated Compounds As Additives In Non-Aqueous Solutions For Electrochemical Cells Novolyte Technologies, Inc. (US) 2012-11-22 US disclosed
EP-0787724-B1 NOVEL INTERMEDIATE FOR PRODUCTION AND PROCESS FOR PRODUCING PYRIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO LTD (JP) 2003-04-16 EP disclosed
US-5734059-A Production intermediate and process for producing pyridine derivative TAIHO PHARMACEUTICAL CO., LTD. (JP) 1998-03-31 US disclosed
EP-0787724-A1 NOVEL INTERMEDIATE FOR PRODUCTION AND PROCESS FOR PRODUCING PYRIDINE DERIVATIVE TAIHO PHARMACEUTICAL CO., LTD. (JP) 1997-08-06 EP disclosed
US-5530134-A Synthesis of anabaseine, salts and derivatives thereof SYNPHAR LABORATORIES INC. (CA) 1996-06-25 US disclosed
EP-0312604-B1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1992-07-08 EP disclosed
EP-0405786-A2 Catalysts IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-02 EP disclosed
US-4908373-A 1-[2-(4-Hydroxybenzoyl)ethanoyl]-2-piperidone and a process for production as well as alcohol fermentation promoter containing the same as effective ingredient TAKI CHEMICAL CO., LTD. (JP) 1990-03-13 US disclosed
EP-0312604-A1 1-(2-(4-HYDROXYBENZOYL)ETHANOYL)-2-PIPERIDONE, PROCESS FOR ITS PREPARATION, AND ALCOHOLIC FERMENTATION ACCELERATOR CONTAINING IT AS EFFECTIVE INGREDIENT TAKI CHEMICAL CO., LTD. (JP) 1989-04-26 EP disclosed
JP-S63264503-A PLANT GROWTH REGULATOR TAKI CHEM CO LTD 1988-11-01 JP disclosed