SCHEMBL11705153

SCHEMBL11705153

CCCCCCCCCC(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.46
SIGMAR1 Q99720 1/20 0.44
HTT P42858 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SLC6A3 Q01959 1/20 0.42
HTR2A P28223 3/20 0.42
HRH3 Q9Y5N1 1/20 0.41
SLC2A1 P11166 1/20 0.41
NR1I2 O75469 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
HRH1 P35367 2/20 0.38
MCHR1 Q99705 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705969 1.00 CYP19A1 (0.46) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL11702009 1.00 CYP19A1 (0.46) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL11702818 1.00 CYP19A1 (0.46) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL11706831 1.00 CYP19A1 (0.46) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL11705344 0.98 CYP19A1 (0.47) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL5271969 0.94 SIGMAR1 (0.53) CYP19A1SIGMAR1MEN1KMT2ANPSR1
SCHEMBL11436698 0.92 SIGMAR1 (0.55) CYP19A1SIGMAR1MEN1KMT2ANPSR1
SCHEMBL27497385 0.91 ACHE (0.45) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL27481974 0.91 ACHE (0.45) CYP19A1SIGMAR1HTTMEN1KMT2A
SCHEMBL10631766 0.91 SIGMAR1 (0.42) CYP19A1SIGMAR1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4022838-A 1,1-DIAR-KETONES, NITRIC ACID, WATER GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-05-10 US disclosed