Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11705203

N.O=C(Oc1ccc2ccccc2c1)c1ccccc1

nearest known ligand 0.96

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.96
MAPT P10636 3/20 0.96
MEN1 O00255 3/20 0.96
TDP1 Q9NUW8 2/20 0.96
CA12 O43570 2/20 0.63
CA9 Q16790 2/20 0.63
POLB P06746 1/20 0.60
PDGFRB P09619 1/20 0.58
PDGFRA P16234 1/20 0.58
ALDH1A1 P00352 2/20 0.58
HSD17B10 Q99714 1/20 0.58
PARP10 Q53GL7 1/20 0.56
MMP1 P03956 2/20 0.54
MMP12 P39900 1/20 0.54
ESR1 P03372 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
PKM P14618 1/20 0.53
MMP2 P08253 1/20 0.53
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639878 0.98 KMT2A (1.00) KMT2AMAPTMEN1TDP1CA12
SCHEMBL30523105 0.98 KMT2A (1.00) KMT2AMAPTMEN1TDP1CA12
SCHEMBL18058690 0.94 KMT2A (0.93) KMT2AMAPTMEN1TDP1CA12
Benzoic Acid SCHEMBL9956914 0.93 KMT2A (0.90) KMT2AMAPTMEN1TDP1CA12
Betanaphthol SCHEMBL16236859 0.90 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
SCHEMBL16236876 0.90 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
SCHEMBL16236336 0.90 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
SCHEMBL27267181 0.89 KMT2A (0.83) KMT2AMAPTMEN1TDP1CA12
SCHEMBL7594572 0.87 KMT2A (0.79) KMT2AMAPTMEN1TDP1CA12
SCHEMBL12925818 0.86 KMT2A (0.78) KMT2AMAPTMEN1TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4051066-A Corrosion-inhibiting rubber and methods of preparation NORTHERN INSTRUMENTS CORPORATION (US) 1977-09-27 US disclosed