SCHEMBL1639878

SCHEMBL1639878

O=C(Oc1ccc2ccccc2c1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 1.00
MAPT P10636 3/20 1.00
MEN1 O00255 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
CA12 O43570 2/20 0.65
CA9 Q16790 2/20 0.65
POLB P06746 1/20 0.62
ALDH1A1 P00352 2/20 0.60
HSD17B10 Q99714 1/20 0.60
PDGFRB P09619 1/20 0.60
PDGFRA P16234 1/20 0.60
PARP10 Q53GL7 1/20 0.58
MMP1 P03956 2/20 0.55
MMP12 P39900 1/20 0.55
ESR1 P03372 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
PKM P14618 1/20 0.54
MMP2 P08253 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30523105 1.00 KMT2A (1.00) KMT2AMAPTMEN1TDP1CA12
Ammonia Solution, Strong SCHEMBL11705203 0.98 KMT2A (0.96) KMT2AMAPTMEN1TDP1CA12
SCHEMBL18058690 0.96 KMT2A (0.93) KMT2AMAPTMEN1TDP1CA12
Benzoic Acid SCHEMBL9956914 0.95 KMT2A (0.90) KMT2AMAPTMEN1TDP1CA12
SCHEMBL16236876 0.92 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
SCHEMBL16236336 0.92 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
Betanaphthol SCHEMBL16236859 0.92 KMT2A (0.84) KMT2AMAPTMEN1TDP1CA12
SCHEMBL27267181 0.91 KMT2A (0.83) KMT2AMAPTMEN1TDP1CA12
SCHEMBL7594572 0.89 KMT2A (0.79) KMT2AMAPTMEN1TDP1CA12
SCHEMBL3911876 0.88 KMT2A (0.78) KMT2AMAPTMEN1TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814467-B Optical film containing optical delay enhancing additive 伊士曼化工公司 2019-04-19 CN claimed
US-9964667-B2 Cellulose ester based quarter wave plates having normal wavelength dispersion EASTMAN CHEMICAL COMPANY (US) 2018-05-08 US claimed
US-9557665-B2 Super low melt toner having crystalline aromatic monoesters XEROX CORPORATION (US) 2017-01-31 US claimed
EP-3084488-A1 OPTICAL FILMS CONTAINING OPTICAL RETARDATION-ENHANCING ADDITIVE Eastman Chemical Company (US) 2016-10-26 EP claimed
CN-105814467-A Optical films containing optical retardation-enhancing additive 伊士曼化工公司 2016-07-27 CN claimed
US-20160187539-A1 CELLULOSE ESTER BASED QUARTER WAVE PLATES HAVING NORMAL WAVELENGTH DISPERSION EASTMAN CHEMICAL COMPANY (US) 2016-06-30 US claimed
US-9309360-B2 Cellulose ester based quarter wave plates having normal wavelength dispersion EASTMAN CHEMICAL COMPANY (US) 2016-04-12 US claimed
US-9309362-B2 Optical films containing optical retardation-enhancing additive EASTMAN CHEMICAL COMPANY (US) 2016-04-12 US claimed
US-20160091808-A1 SUPER LOW MELT TONER HAVING CRYSTALLINE AROMATIC MONOESTERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2016-03-31 US claimed
US-9285694-B2 Super low melt toner having crystalline aromatic monoesters XEROX CORPORATION (US) 2016-03-15 US claimed
US-20150168608-A1 OPTICAL FILMS CONTAINING OPTICAL RETARDATION-ENHANCING ADDITIVE EASTMAN CHEMICAL COMPANY (US) 2015-06-18 US claimed
US-20150168607-A1 CELLULOSE ESTER BASED QUARTER WAVE PLATES HAVING NORMAL WAVELENGTH DISPERSION EASTMAN CHEMICAL COMPANY (US) 2015-06-18 US claimed
US-20150132695-A1 SUPER LOW MELT TONER HAVING CRYSTALLINE AROMATIC MONOESTERS XEROX CORPORATION (US) 2015-05-14 US claimed
US-20140168770-A1 MULTILAYER AND SINGLE LAYER CELLULOSE ESTER FILMS HAVING REVERSED OPTICAL DISPERSION EASTMAN CHEMICAL COMPANY (US) 2014-06-19 US claimed
CN-103768754-A Fire-extinguishment composition containing unsaturated hydrocarbon compounds and derivatives thereof XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY 2014-05-07 CN claimed
US-7728096-B2 Adhesive having aromatic diisocyanates and aromatic petroleum distillates with low volatility for use in engineered wood products WEYERHAEUSER NR COMPANY (US) 2010-06-01 US claimed
US-20080135173-A1 Adhesive Having Aromatic Diisocyanates And Aromatic Petroleum Distillates With Low Volatility For Use In Engineered Wood Products WEYERHAEUSER CO. (US) 2008-06-12 US claimed
JP-57064593-A None JP disclosed
US-4036227-A Osmotic releasing device having a plurality of release rate patterns ALZA CORPORATION (US) 1977-07-19 US disclosed
US-3956209-A POLYSILOXANES, ALKYL SILICATES, FILLERS GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed