Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28716667 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10FFAR3LCK | |
| SCHEMBL1683664 | 0.95 | — | — | |
| SCHEMBL27948229 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL27845804 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL28250755 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL28781241 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL28026699 | 0.92 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRTDP1 | |
| SCHEMBL27824742 | 0.85 | ALDH1A1 (0.35) | ALDH1A1LMNAHSD17B10 | |
| Acetoacetic Acid SCHEMBL27726728 | 0.84 | KDM4E (0.35) | ALDH1A1LMNAHSD17B10FFAR3TDP1 | |
| SCHEMBL662739 | 0.78 | LMNA (0.48) | ALDH1A1LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101927002-B | Medicament and coating composition | ZHONG SHUGUANG | 2014-03-12 | — | — | CN | claimed |
| CN-103432091-A | Improved-performance tablet and preparation method thereof | ZHONG SHUGUANG | 2013-12-11 | — | — | CN | claimed |
| CN-101987081-B | Controlled release preparation | SHUGUANG ZHONG | 2012-08-08 | — | — | CN | claimed |
| CN-102000344-A | Medicament coating composition with masked taste | SHUGUANG ZHONG | 2011-04-06 | — | — | CN | claimed |
| CN-101987081-A | Controlled release preparation | SHUGUANG ZHONG | 2011-03-23 | — | — | CN | claimed |
| CN-101985044-A | Taste-masking medicinal coating composition | SHUGUANG ZHONG | 2011-03-16 | — | — | CN | claimed |
| CN-101927002-A | Medicament and coating composition | SHUGUANG ZHONG | 2010-12-29 | — | — | CN | claimed |
| US-5008118-A | Contacting coating agent with core powder of organic material with sufficient frictional heating to cause adhesion | NIPPON OIL AND FATS (JP) | 1991-04-16 | — | — | US | claimed |
| EP-3826619-A1 | PHARMACEUTICAL DOSAGE FORM WHICH CAN BE ADMINISTERED ORALLY AND HAS MODIFIED RELEASE | Bayer Aktiengesellschaft (DE) | 2021-06-02 | — | — | EP | disclosed |
| EP-3826627-A1 | PHARMACEUTICAL DOSAGE FORM WHICH CAN BE ADMINISTERED ORALLY AND HAS MODIFIED RELEASE | Bayer Aktiengesellschaft (DE) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020020790-A1 | PHARMACEUTICAL DOSAGE FORM WHICH CAN BE ADMINISTERED ORALLY AND HAS MODIFIED RELEASE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | WO | disclosed |
| WO-2020020789-A1 | PHARMACEUTICAL DOSAGE FORM WHICH CAN BE ADMINISTERED ORALLY AND HAS MODIFIED RELEASE | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | WO | disclosed |
| EP-2392326-B9 | Silibinin component for the treatment of hepatitis | MADAUS GMBH (DE) | 2018-09-05 | — | — | EP | disclosed |
| EP-2392326-B1 | Silibinin component for the treatment of hepatitis | MADAUS GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| EP-0335560-A2 | Controlled release pharmaceutical preparation and method for producing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1989-10-04 | — | — | EP | disclosed |
| US-4842863-A | PHYSIOLOGICALLY ACTIVE SUBSTANCE COATED WITH A THIN FILM OF WAXY SUBSTANCE CONTAINING A SOLID AUXILIARY SUBSTANCE | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0276781-A2 | Granular agent for ruminant and production method thereof | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1988-08-03 | — | — | EP | disclosed |
| US-4285987-A | Process for manufacturing device with dispersion zone | ALZA CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |
| US-4200098-A | Osmotic system with distribution zone for dispensing beneficial agent | ALZA CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |
| US-4160020-A | CELLULOSE ESTERS, CELLULOSE ETHERS | ALZA CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |