Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767592 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL11766715 | 0.90 | ALDH1A1 (0.42) | ALDH1A1TSHRHPGDHSD17B10HDAC6 | |
| SCHEMBL11766297 | 0.89 | ALDH1A1 (0.55) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL11767478 | 0.87 | TSHR (0.61) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL11765127 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL11767782 | 0.85 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1KMT2APKM | |
| SCHEMBL11766972 | 0.85 | TSHR (0.70) | ALDH1A1TSHRHTTMEN1KMT2A | |
| SCHEMBL11766501 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TSHRHTTASAH1 | |
| SCHEMBL11773243 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL202952 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031234-A | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-06-21 | — | — | US | claimed |
| US-4031234-A | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3993769-A | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-11-23 | — | — | US | disclosed |