Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11708320 | 0.86 | P2RY6 (0.44) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11709012 | 0.86 | P2RY6 (0.44) | L3MBTL1RAB9AGAASMN1; SMN2LMNA | |
| SCHEMBL11710912 | 0.86 | NPC1 (0.43) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11713450 | 0.82 | MAPK1 (0.42) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11711212 | 0.80 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2AGAALMNA | |
| SCHEMBL11711094 | 0.78 | KMT2A (0.46) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11710026 | 0.76 | P2RY6 (0.43) | NPC1RAB9ASMN1; SMN2LMNAP2RY6 | |
| SCHEMBL11704005 | 0.74 | P2RY6 (0.42) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11708342 | 0.74 | P2RY6 (0.46) | L3MBTL1NPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL11709891 | 0.74 | P2RY6 (0.41) | MEN1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001254-A | ISOTHIOCYANOPYRIDINE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |