Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705656 | 0.86 | L3MBTL1 (0.45) | P2RY6L3MBTL1GAAALDH1A1RAB9A | |
| SCHEMBL11708320 | 0.86 | P2RY6 (0.44) | P2RY6L3MBTL1ALDH1A1POLBRAB9A | |
| SCHEMBL11710912 | 0.86 | NPC1 (0.43) | P2RY6HSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL11711554 | 0.78 | HAO1 (0.41) | P2RY6HSD17B10ALDH1A1MAOBCDC7 | |
| SCHEMBL11710026 | 0.76 | P2RY6 (0.43) | P2RY6HSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL11710596 | 0.74 | P2RY6 (0.42) | P2RY6RAB9ASMN1; SMN2MAOBLMNA | |
| SCHEMBL11708342 | 0.74 | P2RY6 (0.46) | P2RY6HSD17B10L3MBTL1GAAALDH1A1 | |
| SCHEMBL11709891 | 0.74 | P2RY6 (0.41) | P2RY6HSD17B10RAB9AMAPTMAPK1 | |
| SCHEMBL11711094 | 0.73 | KMT2A (0.46) | L3MBTL1GAAALDH1A1POLBRAB9A | |
| SCHEMBL11708832 | 0.72 | P2RY6 (0.40) | P2RY6HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001254-A | ISOTHIOCYANOPYRIDINE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |