SCHEMBL11705753

SCHEMBL11705753

Cc1cc(OCCO)c(C)c(C)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.39
AOC3 Q16853 1/20 0.39
ALDH1A1 P00352 5/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
IKBKB O14920 1/20 0.36
TUBB1 Q9H4B7 1/20 0.36
HTR7 P34969 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
IDO1 P14902 1/20 0.33
DHPS P49366 2/20 0.32
HTR1A P08908 1/20 0.32
BRD4 O60885 1/20 0.32
RECQL P46063 1/20 0.31
ALOX5AP P20292 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11705762 0.91 IKBKB (0.37) LOXAOC3ALDH1A1TP53CYP3A4
SCHEMBL25236092 0.78 POLB (0.42) LOXAOC3ALDH1A1TP53TSHR
SCHEMBL30464802 0.78 POLB (0.42) LOXAOC3ALDH1A1TP53TSHR
SCHEMBL4815160 0.78 TP53 (0.44) LOXAOC3ALDH1A1TP53TUBB1
SCHEMBL13324328 0.78 LOX (0.42) LOXAOC3ALDH1A1TSHRTDP1
SCHEMBL455549 0.76 ALDH1A1 (0.41) LOXAOC3ALDH1A1TP53CYP3A4
SCHEMBL29353325 0.76 ALDH1A1 (0.41) LOXAOC3ALDH1A1TP53CYP3A4
SCHEMBL11706798 0.76 TSHR (0.43) LOXAOC3ALDH1A1TP53CYP3A4
SCHEMBL11706025 0.75 TP53 (0.46) ALDH1A1TP53CYP3A4TSHRTDP1
Hydrochloric Acid SCHEMBL10361244 0.74 ALDH1A1 (0.40) LOXAOC3ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4036824-A Disazo dyestuffs containing A-O-alkylene-O-SO3 H group BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-3956267-A Indole-containing disazo dyestuffs having a sulfatoalkyleneoxy-substituent BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed