Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25236092 | 1.00 | POLB (0.42) | POLBIDO1LOXAOC3TUBB1 | |
| SCHEMBL2939579 | 0.87 | IDO1 (0.41) | POLBIDO1LOXAOC3TUBB1 | |
| SCHEMBL8527585 | 0.80 | IDO1 (0.39) | POLBIDO1LOXAOC3TUBB1 | |
| SCHEMBL11768488 | 0.79 | IDO1 (0.41) | POLBIDO1LOXAOC3TUBB1 | |
| SCHEMBL28319284 | 0.79 | POLB (0.46) | POLBAOC3ALDH1A1TSHRKMT2A | |
| SCHEMBL11705753 | 0.78 | LOX (0.39) | IDO1LOXAOC3TUBB1ALDH1A1 | |
| SCHEMBL10633040 | 0.78 | ALDH1A1 (0.44) | IDO1ALDH1A1RECQLHTR1BTSHR | |
| SCHEMBL29869475 | 0.76 | POLB (0.43) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL23903581 | 0.76 | POLB (0.43) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL11704652 | 0.74 | KDM4E (0.47) | POLBIDO1TUBB1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114977-A1 | S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | TIAKI THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |