Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584465 | 0.86 | HSP90AB1 (0.43) | HSP90AB1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27670497 | 0.86 | HSP90AB1 (0.43) | HSP90AB1RAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7532562 | 0.83 | ALDH1A1 (0.48) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8204240 | 0.83 | MAPT (0.46) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL27589542 | 0.83 | GABRA1 (0.41) | HSP90AB1 | |
| SCHEMBL27787720 | 0.83 | HSP90AB1 (0.41) | HSP90AB1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10430333 | 0.83 | PPARA (0.48) | HSP90AB1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL7139165 | 0.82 | PPARA (0.54) | ALDH1A1 | |
| SCHEMBL28277679 | 0.81 | IKBKB (0.42) | RAB9AMAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6174178 | 0.81 | HSP90AB1 (0.48) | HSP90AB1RAB9AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101337945-B | 4-acetamino-3-(4-arylthiazole-2-amino)benzoate, method for preparing same and applications | UNIV HUNAN | 2010-08-18 | — | — | CN | disclosed |
| CN-101337945-A | 4-acetamino-3-(4-arylthiazole-2-amino)benzoate, method for preparing same and applications | UNIV HUNAN (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-1867571-A | In situ preparation of chiral derivatives of oxaborolidine-borane complexes, useful in asymmetric reduction reactions of etheroximes or ketones to chiral alcohols or amines | PPG SIPSY (FR) | 2006-11-22 | — | — | CN | disclosed |
| US-4025558-A | SPIRO(CYCLOHEXANE-1,1*(2'H)-NAPHTHALENE); BENZOSPIRAN DERIVATIVES; CNS DEPRESSANTS, LOWERS BLOOD PRESSURE | THE UPJOHN COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-4010201-A | AMINOBENZOSPIRANS, CENTRAL NERVOUS SYSTEM DEPRESSANT, HYPOTENSIVE | THE UPJOHN COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-3932425-A | CNS DEPRESSANT, BLOOD PRESSURE LOWERING | THE UPJOHN COMPANY (US) | 1976-01-13 | — | — | US | disclosed |