Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706114 | 1.00 | ALDH1A1 (0.35) | ALDH1A1TP53L3MBTL1PELI1KEAP1 | |
| SCHEMBL28199586 | 0.87 | TSHR (0.46) | ALDH1A1TP53L3MBTL1TSHR | |
| SCHEMBL23057502 | 0.83 | — | — | |
| SCHEMBL4591815 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TP53L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL264926 | 0.78 | — | — | |
| SCHEMBL295221 | 0.78 | — | — | |
| SCHEMBL4559860 | 0.78 | — | — | |
| SCHEMBL104240 | 0.78 | — | — | |
| SCHEMBL2540688 | 0.78 | — | — | |
| SCHEMBL23900957 | 0.75 | HDAC3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052362-A | N-CINNAMOYL-N'-ACYLHYDRAZINES | UBE INDUSTRIES, LTD. (JA) | 1977-10-04 | — | — | US | disclosed |