SCHEMBL4591815

SCHEMBL4591815

C/C=C/C(=O)NC(=O)/C=C/C

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
APEX1 P27695 1/20 0.33
CNR2 P34972 8/20 0.32
CNR1 P21554 6/20 0.32
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
TSHR P16473 1/20 0.32
TGM2 P21980 1/20 0.32
TRPA1 O75762 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10407848 0.88 ALDH1A1 (0.33) ALDH1A1TP53L3MBTL1SMN1; SMN2KEAP1
SCHEMBL5409266 0.88
SCHEMBL10407850 0.88 ALDH1A1 (0.33) ALDH1A1TP53L3MBTL1SMN1; SMN2KEAP1
SCHEMBL5409269 0.88
SCHEMBL18424029 0.87 TSHR (0.46) ALDH1A1TP53L3MBTL1SMN1; SMN2TSHR
SCHEMBL28329887 0.87 TSHR (0.46) ALDH1A1TP53L3MBTL1SMN1; SMN2TSHR
SCHEMBL13497222 0.85
SCHEMBL10536655 0.85
SCHEMBL19390594 0.83 ALDH1A1 (0.32) ALDH1A1TP53L3MBTL1SMN1; SMN2
SCHEMBL13886584 0.83 ALDH1A1 (0.32) ALDH1A1TP53L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371454-B2 Imageable element comprising sulfated polymers EASTMAN KODAK COMPANY (US) 2008-05-13 US disclosed
EP-1641619-B1 IMAGEABLE ELEMENT COMPRISING SULFATED POLYMERS EASTMAN KODAK CO (US) 2006-12-13 EP disclosed
US-7049047-B2 Imageable element with masking layer comprising sulfated polymer EASTMAN KODAK COMPANY (US) 2006-05-23 US disclosed
EP-1641619-A1 IMAGEABLE ELEMENT COMPRISING SULFATED POLYMERS Kodak Polychrome Graphics LLC (US) 2006-04-05 EP disclosed
US-20060035166-A1 Imageable element with masking layer comprising sulfated polymer CITICORP NORTH AMERICA, INC., AS AGENT 2006-02-16 US disclosed
US-20050129915-A1 Imageable element comprising sulfated polymers KODAK (NEAR EAST) INC. 2005-06-16 US disclosed
WO-2005005146-A1 IMAGEABLE ELEMENT COMPRISING SULFATED POLYMERS KODAK POLYCHROME GRAPHICS LLC (US) 2005-01-20 WO disclosed