Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798525 | 0.90 | KDM4E (0.46) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL13346339 | 0.82 | LMNA (0.47) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL17165985 | 0.81 | KDM4E (0.46) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL32688754 | 0.81 | KDM4E (0.46) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL11706641 | 0.80 | KDM4E (0.49) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL12326366 | 0.80 | KDM4E (0.49) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL17165983 | 0.79 | KDM4E (0.45) | KDM4ELMNAEPHX2ALDH1A1KMT2A | |
| SCHEMBL8852595 | 0.79 | LMNA (0.47) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL13346338 | 0.78 | KDM4E (0.50) | KDM4ELMNATHRBEPHX2ALDH1A1 | |
| SCHEMBL14400824 | 0.78 | LMNA (0.51) | KDM4ELMNATHRBEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044054-A | 2-Oxo-3-alkenyl dimethylamine | CALGON CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |