Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798525 | 0.83 | KDM4E (0.46) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL11706113 | 0.80 | KDM4E (0.44) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL4741806 | 0.79 | KDM4E (0.53) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL14581091 | 0.79 | KDM4E (0.62) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL13346338 | 0.76 | KDM4E (0.50) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL32689204 | 0.76 | KDM4E (0.55) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL5357666 | 0.76 | KDM4E (0.53) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL11708853 | 0.76 | KDM4E (0.53) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL14221813 | 0.75 | KDM4E (0.53) | KDM4ELMNATHRBALDH1A1HPGD | |
| SCHEMBL5358926 | 0.75 | KDM4E (0.49) | KDM4ELMNATHRBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044054-A | 2-Oxo-3-alkenyl dimethylamine | CALGON CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |