Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706084 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| Hydrochloric Acid SCHEMBL9657714 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL6960006 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL6960011 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL9795083 | 0.83 | ALDH1A1 (0.48) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL11259398 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL11259402 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL10913779 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2TDP1ALDH1A1MAPTTP53 | |
| SCHEMBL6956520 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2TDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL4384277 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2TDP1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008239-A | Preparation of 4-(3-nitrophenyl)pyridine | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | claimed |
| US-3970662-A | 4-(3-Nitrophenyl)-2,3,5,6-pyridinetetracarboxylic acid and intermediates | STERLING DRUG INC. (US) | 1976-07-20 | — | — | US | claimed |
| US-4055588-A | Tetra-(lower-alkyl)3-(3-nitrophenyl)-1,5-pentanedione-1,2,4,5-tetracarboxylates | STERLING DRUG INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4008239-A | Preparation of 4-(3-nitrophenyl)pyridine | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3970662-A | 4-(3-Nitrophenyl)-2,3,5,6-pyridinetetracarboxylic acid and intermediates | STERLING DRUG INC. (US) | 1976-07-20 | — | — | US | disclosed |