Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 9/20 | 0.36 |
| ▸ | CNR2 | P34972 | 9/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705589 | 0.87 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL11703604 | 0.81 | CA1 (0.37) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL11318649 | 0.78 | KDM4E (0.37) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL11662767 | 0.76 | TSHR (0.41) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL11705406 | 0.75 | ESR1 (0.41) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL36429 | 0.75 | KDM4E (0.43) | KDM4EMEN1MAPTKMT2AJAK2 | |
| SCHEMBL6361815 | 0.74 | FEN1 (0.37) | CNR1CNR2 | |
| SCHEMBL16270481 | 0.74 | PTGDR2 (0.40) | KDM4EMEN1MAPTKMT2APTGDR2 | |
| SCHEMBL10956529 | 0.74 | KDM4E (0.46) | KDM4EMEN1MAPTKMT2AJAK2 | |
| SCHEMBL11705962 | 0.74 | PTGDR2 (0.41) | KDM4EMEN1MAPTKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013473-A | THERMOGRAPHY, SUBSTITUTED PHENOL REDUCING AGENT | AGFA-GEVAERT N.V. (BE) | 1977-03-22 | — | — | US | disclosed |