Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705962 | 0.98 | PTGDR2 (0.41) | ESR1ESR2PTGDR2NUDT1BACE1 | |
| SCHEMBL1087151 | 0.79 | KDM4E (0.49) | ESR1ESR2PTGDR2NUDT1BACE1 | |
| SCHEMBL9804702 | 0.77 | ESR1 (0.41) | ESR1ESR2PTGDR2NUDT1BACE1 | |
| SCHEMBL11705384 | 0.77 | ESR1 (0.41) | ESR1ESR2PTGDR2NUDT1BACE1 | |
| SCHEMBL3436090 | 0.76 | PTGDR2 (0.41) | PTGDR2PSMB5NR1I2KDM4BCHRM1 | |
| SCHEMBL11706304 | 0.75 | KDM4E (0.39) | PTGDR2NUDT1BACE1HSP90AA1KDM4E | |
| SCHEMBL28386966 | 0.75 | KDM4E (0.39) | PTGDR2NUDT1BACE1HSP90AA1KDM4E | |
| SCHEMBL2219921 | 0.75 | NUDT1 (0.42) | PTGDR2NUDT1BACE1HSP90AA1KDM4E | |
| SCHEMBL11701220 | 0.75 | ESR1 (0.40) | ESR1ESR2PTGDR2NUDT1BACE1 | |
| SCHEMBL9785240 | 0.75 | PTGDR2 (0.41) | ESR1ESR2PTGDR2NUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059563-A | ANTIDEGRADATION | NIPPON ZEON CO. LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| US-4008284-A | ANTIDEGRADATION | NIPPON ZEON CO., LTD. (JA) | 1977-02-15 | — | — | US | claimed |
| US-20200133121-A1 | ONIUM SALT, NEGATIVE RESIST COMPOSITION, AND RESIST PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-04-30 | — | — | US | disclosed |
| US-4059563-A | ANTIDEGRADATION | NIPPON ZEON CO. LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4008284-A | ANTIDEGRADATION | NIPPON ZEON CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200133121-A1 | ONIUM SALT, NEGATIVE RESIST COMPOSITION, AND RESIST PATTERN FORMING PROCESS | SLC6A5, SLC11A2, LARP7 | ESR1 1702/4885ESR2 1219/4885PTGDR2 4138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.