SCHEMBL11318649

SCHEMBL11318649

Cc1c(C2CCCC2)cc(C2CCCC2)c(O)c1Cc1c(C)c(C2CCCC2)cc(C2CCCC2)c1O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
NUDT1 P36639 1/20 0.34
BACE1 P56817 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.33
CNR1 P21554 3/20 0.31
CNR2 P34972 3/20 0.31
HSP90AA1 P07900 1/20 0.31
PSMB5 P28074 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11310170 0.79 KDM4E (0.36) KDM4EMEN1MAPTKMT2ACYP2C9
SCHEMBL10697033 0.79 MEN1 (0.39) KDM4EMEN1MAPTKMT2ACYP2C9
SCHEMBL11706304 0.78 KDM4E (0.39) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL15253180 0.73 KDM4E (0.40) KDM4EMEN1MAPTKMT2ATP53
SCHEMBL36429 0.72 KDM4E (0.43) KDM4EMEN1MAPTKMT2ATP53
SCHEMBL11705406 0.72 ESR1 (0.41) KDM4EMEN1MAPTKMT2ANUDT1
SCHEMBL14431782 0.72 AMY1A (0.39) KDM4EMEN1MAPTKMT2ATP53
SCHEMBL11595709 0.71 AMY1A (0.44) KDM4EMEN1MAPTKMT2ATP53
SCHEMBL11705962 0.71 PTGDR2 (0.41) KDM4EMEN1MAPTKMT2ATP53
SCHEMBL11625563 0.71 NUDT1 (0.46) KDM4EMEN1MAPTKMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed