Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484520 | 0.83 | KDM4E (0.39) | RAB9ASMN1; SMN2MAPTNR1H3NPC1 | |
| SCHEMBL11709729 | 0.83 | NPC1 (0.44) | CYP1A2MAPTKMT2ANPC1TP53 | |
| SCHEMBL11488725 | 0.83 | NPC1 (0.47) | SMN1; SMN2MAPTKMT2ANPC1GRM5 | |
| SCHEMBL11709204 | 0.82 | TP53 (0.45) | CYP1A2RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11709818 | 0.80 | NR1H3 (0.42) | NR1H3GRM5KDM4EALDH1A1GAA | |
| SCHEMBL1922080 | 0.77 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2KMT2ANPC1TP53 | |
| SCHEMBL11705831 | 0.76 | ALDH1A1 (0.50) | RAB9ASMN1; SMN2MAPTKMT2ATP53 | |
| SCHEMBL11608858 | 0.72 | NPC1 (0.54) | SMN1; SMN2MAPTKMT2ANPC1KDM4E | |
| SCHEMBL11548784 | 0.72 | HTR1A (0.51) | CYP1A2RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL30046397 | 0.72 | HTR1A (0.51) | CYP1A2RAB9ASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038391-A | TRANQUILIZERS, ANTICONVULSANTS | RHONE-POULENC S.A. (FR) | 1977-07-26 | — | — | US | disclosed |
| US-4016274-A | TRANQUILIZERS AND ANTICONVULSANT AGENTS | RHONE-POULENC S.A. (FR) | 1977-04-05 | — | — | US | disclosed |