Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705493 | 0.77 | KDM4E (0.37) | ABL1ALDH1A1KDM4EMAP3K5 | |
| SCHEMBL11354763 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTKDM4EMAP3K5GAA | |
| SCHEMBL3160944 | 0.75 | ADORA1 (0.47) | ALDH1A1MAP3K5GAAMAPK1 | |
| SCHEMBL27494779 | 0.69 | GAA (0.57) | ALDH1A1KDM4EGAA | |
| SCHEMBL28335465 | 0.67 | KDM4E (0.41) | ALDH1A1KDM4EMAP3K5 | |
| SCHEMBL13134172 | 0.67 | EGFR (0.46) | KDM4E | |
| SCHEMBL11348714 | 0.67 | CCNE1 (0.44) | ALDH1A1KDM4EMAP3K5 | |
| SCHEMBL24349063 | 0.67 | TGFBR1 (0.44) | ABL1ALDH1A1HTTMAPK14GAA | |
| Potassium Ion SCHEMBL28282527 | 0.67 | KDM4E (0.38) | ALDH1A1KDM4EMAP3K5SCN1ASCN5A | |
| SCHEMBL26722263 | 0.65 | RIOK2 (0.48) | ABL1ALDH1A1HTTMAPK14GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011210-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
| US-3939172-A | OR 4-TRIFLUOROACETAMIDO-THIAZOLE OR SALTS, INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |