Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710002 | 0.93 | CNR1 (0.48) | HTR2AHTR2CMAPTMCOLN3C5AR1 | |
| SCHEMBL11708553 | 0.92 | CNR1 (0.49) | HTR2AHTR2CMAPTMCOLN3NPSR1 | |
| SCHEMBL11706992 | 0.87 | CNR1 (0.46) | HTR2AHTR2CMAPTMCOLN3C5AR1 | |
| SCHEMBL11705624 | 0.83 | CNR1 (0.48) | HTR2AHTR2CMAPTMCOLN3C5AR1 | |
| SCHEMBL11709606 | 0.81 | CNR1 (0.49) | HTR2AHTR2CMAPTMCOLN3NPSR1 | |
| SCHEMBL28659013 | 0.72 | HTR2A (0.48) | HTR2AHTR2CMAPTMCOLN3C5AR1 | |
| SCHEMBL3699604 | 0.71 | POLB (0.54) | HTR2AHTR2CMAPTMCOLN3AGER | |
| SCHEMBL6822180 | 0.71 | MAPT (0.59) | HTR2AHTR2CMAPTMCOLN3C5AR1 | |
| SCHEMBL9303072 | 0.70 | ALDH1A1 (0.73) | HTR2AHTR2CMAPTMCOLN3NPSR1 | |
| SCHEMBL3189975 | 0.70 | MAPT (0.57) | MAPTMCOLN3C5AR1AGERCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022828-A | BIS-(SULFONAMIDO)-SULFIDES | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |