SCHEMBL11706992

SCHEMBL11706992

Cc1ccc(S(=O)(=O)N(SSSN(C2CCCC2)S(=O)(=O)c2ccc(C)cc2)C2CCCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.46
CNR2 P34972 2/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
POLB P06746 1/20 0.45
ALDH1A1 P00352 7/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ACHE P22303 1/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
BACE1 P56817 1/20 0.42
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 3/20 0.41
TP53 P04637 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11710002 0.94 CNR1 (0.48) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL11708553 0.92 CNR1 (0.49) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL11705624 0.87 CNR1 (0.48) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL11707463 0.87 HTR2A (0.50) CNR1CNR2HTR2AHTR2CALDH1A1
SCHEMBL11709606 0.86 CNR1 (0.49) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL3699604 0.77 POLB (0.54) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL9303072 0.76 ALDH1A1 (0.73) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL11116465 0.74 CNR1 (0.50) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL3280160 0.74 POLB (0.54) CNR1CNR2HTR2AHTR2CPOLB
SCHEMBL29165184 0.72 CNR1 (0.48) CNR1CNR2HTR2AHTR2CPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4022828-A BIS-(SULFONAMIDO)-SULFIDES UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-05-10 US disclosed