Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140445 | 0.75 | ALDH1A1 (0.51) | CYP3A4MAPK1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL5459454 | 0.74 | MAP2K1 (0.54) | CYP3A4MAPK1ALDH1A1HPGDKMT2A | |
| SCHEMBL5838887 | 0.73 | CYP3A4 (0.58) | CYP3A4MAPK1SMN1; SMN2USP2HTT | |
| SCHEMBL11712521 | 0.72 | LMNA (0.54) | CYP3A4MAPK1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11708668 | 0.70 | ALDH1A1 (0.37) | SMN1; SMN2HTTALDH1A1HPGDLMNA | |
| SCHEMBL3429136 | 0.69 | SRC (0.49) | CYP3A4MAPK1SMN1; SMN2USP2PDE3B | |
| SCHEMBL7691286 | 0.69 | MAPK1 (0.42) | CYP3A4MAPK1ALDH1A1HPGDKMT2A | |
| SCHEMBL25999943 | 0.69 | DPP4 (0.47) | CYP3A4SMN1; SMN2DPP4ALDH1A1HPGD | |
| SCHEMBL2204818 | 0.68 | ESR2 (0.45) | CYP3A4MAPK1SMN1; SMN2USP2PDE3B | |
| SCHEMBL29549879 | 0.68 | EGFR (0.42) | ALDH1A1HPGDPDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010270-A | ANTIALLERGENS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |