Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465968 | 0.86 | TDP1 (0.38) | MAOBKMT2AALDH1A1TDP1LMNA | |
| SCHEMBL14037017 | 0.81 | CA1 (0.31) | MAOBTDP1 | |
| SCHEMBL3628711 | 0.80 | LTA4H (0.33) | MAOBTDP1 | |
| SCHEMBL1466000 | 0.80 | LTA4H (0.33) | MAOBTDP1 | |
| SCHEMBL3628714 | 0.80 | LTA4H (0.33) | MAOBTDP1 | |
| SCHEMBL195629 | 0.79 | LTA4H (0.43) | KMT2AALDH1A1TDP1 | |
| SCHEMBL5598440 | 0.78 | LTA4H (0.32) | MAOBTDP1 | |
| SCHEMBL11705999 | 0.78 | ALDH1A1 (0.42) | MAOBKMT2AALDH1A1TDP1RAB9A | |
| SCHEMBL6244032 | 0.77 | MAOB (0.48) | MAOBKMT2AIDO1EGFRALDH1A1 | |
| SCHEMBL11702182 | 0.77 | PPARG (0.41) | KMT2AIDO1TDO2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025570-A | REACTION OF ETHYLENE WITH 1,3-DIENE; CATALYST OF NICKEL, HYDROCARBYLALUMINUM HALIDE, AND ARYL PHOSPHINITE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-05-24 | — | — | US | disclosed |