Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909319 | 0.85 | NUDT1 (0.39) | NUDT1BACE1HSP90AA1CNR1CNR2 | |
| SCHEMBL11764867 | 0.83 | NUDT1 (0.41) | NUDT1BACE1HSP90AA1CNR1CNR2 | |
| SCHEMBL4609516 | 0.82 | NUDT1 (0.40) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL6863507 | 0.82 | NUDT1 (0.44) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL7861267 | 0.82 | NUDT1 (0.44) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL4608024 | 0.81 | NUDT1 (0.42) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL30152751 | 0.81 | NUDT1 (0.42) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL1160572 | 0.80 | NUDT1 (0.45) | NUDT1BACE1HSP90AA1CNR1CNR2 | |
| SCHEMBL11319506 | 0.78 | NUDT1 (0.44) | NUDT1BACE1HSP90AA1HDAC4HDAC2 | |
| SCHEMBL17666843 | 0.78 | HTR2C (0.46) | NUDT1BACE1HSP90AA1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059563-A | ANTIDEGRADATION | NIPPON ZEON CO. LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4008284-A | ANTIDEGRADATION | NIPPON ZEON CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |