SCHEMBL4608024

SCHEMBL4608024

Cc1c(O)ccc(C2CCCCC2)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.42
BACE1 P56817 1/20 0.42
HSP90AA1 P07900 1/20 0.42
FEN1 P39748 3/20 0.39
ACMSD Q8TDX5 2/20 0.38
ADRB2 P07550 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
CEL P19835 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX5AP P20292 2/20 0.36
PTPN5 P54829 2/20 0.35
PTPN2 P17706 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152751 1.00 NUDT1 (0.42) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL4609516 0.98 NUDT1 (0.40) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL7861267 0.86 NUDT1 (0.44) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL6863507 0.86 NUDT1 (0.44) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL10607806 0.82 NUDT1 (0.46) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL4301114 0.81 HTR2C (0.44) NUDT1BACE1HSP90AA1HDAC4HDAC2
SCHEMBL11709403 0.81 NUDT1 (0.39) NUDT1BACE1HSP90AA1ACMSDADRB2
SCHEMBL8954635 0.81 HTR2C (0.44) NUDT1BACE1HSP90AA1HDAC4HDAC2
SCHEMBL11764867 0.79 NUDT1 (0.41) NUDT1BACE1HSP90AA1FEN1ACMSD
SCHEMBL28645757 0.79 NUDT1 (0.45) NUDT1BACE1HSP90AA1FEN1ACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101184722-B Novel resorcinol derivatives for skin UNILEVER NV 2011-06-22 CN claimed
US-7468464-B2 Resorcinol derivatives for skin UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2008-12-23 US claimed
EP-1861353-B1 NOVEL RESORCINOL DERIVATIVES FOR SKIN UNILEVER PLC (GB) 2008-10-08 EP claimed
US-20080131382-A1 Novel Resorcinol Derivatives for Skin UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2008-06-05 US claimed
CN-101184722-A Novel resorcinol derivatives for skin UNILEVER HOME & PERSONAL CARE (NL) 2008-05-21 CN claimed
CN-101175711-A Novel resorcinol derivatives UNILEVER PLC (NL) 2008-05-07 CN claimed
EP-1861353-A1 NOVEL RESORCINOL DERIVATIVES FOR SKIN UNILEVER PLC (GB) 2007-12-05 EP claimed
EP-1858835-A1 NOVEL RESORCINOL DERIVATIVES UNILEVER PLC (GB) 2007-11-28 EP claimed
US-20060210498-A1 Novel resorcinol derivatives for skin UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-09-21 US claimed
WO-2006097223-A1 NOVEL RESORCINOL DERIVATIVES UNILEVER PLC (GB) 2006-09-21 WO claimed
WO-2006097224-A1 NOVEL RESORCINOL DERIVATIVES FOR SKIN UNILEVER PLC (GB) 2006-09-21 WO claimed
US-20060210497-A1 Novel resorcinol derivatives UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-09-21 US claimed
US-20220073736-A1 POLYCARBONATE COMPOSITION, PREPARATION METHOD AND APPLICATION THEREOF KINGFA SCI. & TECH. CO., LTD. (CN) 2022-03-10 US disclosed
EP-3889219-A1 POLYCARBONATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF KINGFA SCI. & TECH. CO., LTD. (CN) 2021-10-06 EP disclosed
CN-109796736-B Polycarbonate composition and preparation method and application thereof 金发科技股份有限公司 2021-05-18 CN disclosed
CN-101184722-B Novel resorcinol derivatives for skin UNILEVER NV 2011-06-22 CN disclosed
US-20060210498-A1 Novel resorcinol derivatives for skin UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-09-21 US disclosed
WO-2006097223-A1 NOVEL RESORCINOL DERIVATIVES UNILEVER PLC (GB) 2006-09-21 WO disclosed
WO-2006097224-A1 NOVEL RESORCINOL DERIVATIVES FOR SKIN UNILEVER PLC (GB) 2006-09-21 WO disclosed
US-20060210497-A1 Novel resorcinol derivatives UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2006-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080131382-A1 Novel Resorcinol Derivatives for Skin NR1H2, CYP1B1, NR0B1 NUDT1 1098/4885BACE1 464/4885HSP90AA1 3078/4885
US-20060210498-A1 Novel resorcinol derivatives for skin NR1H2, CYP1B1, NR0B1 NUDT1 1098/4885BACE1 464/4885HSP90AA1 3078/4885
US-20060210497-A1 Novel resorcinol derivatives NR1H2, DEGS1, NR1H3 NUDT1 1482/4885BACE1 369/4885HSP90AA1 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.